KMID : 0359919920110020159
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Korean Journal of Nephrology 1992 Volume.11 No. 2 p.159 ~ p.166
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Evolution of Serum Ferrtin Levels after Renal Transplantation
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À̼öÇü/±èÇöö/Á¶¿øÇö/¹ÚöÈñ/Àüµ¿¼®
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Abstract
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A prospective study was made of the evolution of serum ferritin levels in 60 renal transplant recipients with good graft function (S. creatinine less than 2.0 mg/dl at 3 month after transplantation). Age ranged from 15 to 58 years (mean ¡¾ SD:
34¡¾10).
Mean duration of follow-up was 19.6¡¾6.0 (12~33) months.
The hemoglobin value increased sharply to normal value 3 months after transplantation with a slow but persistent rise until 12 months after transplantation (p<0.001). Serum ferrtin level rapidly decreased to normal range 6 months after
transplantation
with a continuous decrease until 18 months(p<0.001).
High basal serum ferritin group (>350 ng/ml) showed a rapid decrease of serum ferritin levels until 9 months after transplantation and there after gradual dereas during follow-up periods. However, lower (<100 ng/ml) and normal (100~350 ng/ml)
basal
serum ferritin groups showed decreased serum ferritin levels abruptly within 3~6 months after transplantation which correlated to a rising of hemoglobin values.
We conclude that evolution of serum ferrifin levels after transplantation is mainly determined by the previous state of iron storage and serum ferritin levels are a good indicator of body iron storage in renal transplant recipients.
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KEYWORD
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